肥大細胞類糜蛋白酶1(CMA1)重組蛋白
Recombinant Chymase 1, Mast Cell (CMA1)
CYH; CYM; Alpha-chymase; Mast cell protease I
- 編號RPG515Ra01
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌
- 預(yù)測分子量23.7kDa
- 實際分子量24kDa(差異分析請參閱說明書)
- 片段與標簽Ile22~Val197 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點9.6
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價格¥ 1128¥ 2820¥ 5640¥ 16920¥ 42300
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. Gene Sequencing (Extract)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPG515Ra01 | 肥大細胞類糜蛋白酶1(CMA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAG515Ra01 | 肥大細胞類糜蛋白酶1(CMA1)多克隆抗體 | WB; IHC; ICC; IP. |
| MAG515Ra21 | 肥大細胞類糜蛋白酶1(CMA1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEG515Ra | 肥大細胞類糜蛋白酶1(CMA1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMG515Ra | 肥大細胞類糜蛋白酶1(CMA1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Pathobiology | Anti-Angiotensin and Hypoglycemic Treatments Suppress Liver Metastasis of Colon Cancer Cells[Karger: 000330169] |
| Clinical and Experimental Metastasis | Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer[PubMed: 22552372] |
| Mediators of Inflammation | Mediators of Mast Cells in Bullous Pemphigoid and Dermatitis Herpetiformis[Pubmed:25400334] |
| Neurogastroenterology & Motility | Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery[Pubmed:25677271] |
| IJC Metab Endocr | The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis[PubMed: 26722642] |
| Journal of?Neuroinflammation | Oral sensitization to whey proteins induces age-and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food?…[Pubmed:29685134] |
| Revista do Instituto de Medicina Tropical de S?o Paulo | Vasoactive intestinal peptide degradation might influence Interleukin-17 expression in cardiac chagasic patients[Pubmed: 30365640] |
| Science Advances | Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury[Pubmed: 32206714] |
| Immunity Inflammation and Disease | Disruption in the balance between apolipoprotein A‐I and mast cell chymase in chronic hypersensitivity pneumonitis[Pubmed: 33016012] |
| Microbiol Spectr | Mast Cell-Derived Proteases Induce Endothelial Permeability and Vascular Damage in Severe Fever with Thrombocytopenia Syndrome[Pubmed:35612327] |