和肽素(CPP)重組蛋白
Recombinant Copeptin (CPP)
C-Terminal Provasopressin; Vasopressin-Neurophysin 2-Copeptin
- 編號(hào)RPA365Mu01
- 物種Mus musculus (Mouse，小鼠)相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位分泌
- 預(yù)測(cè)分子量34.2kDa
- 實(shí)際分子量37kDa(差異分析請(qǐng)參閱說明書)
- 片段與標(biāo)簽Ala130~Tyr168 with N-terminal His and GST Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)10.4
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA365Mu01 | 和肽素(CPP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| CEA365Mu | 和肽素(CPP)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA365Mu | 和肽素(CPP)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Med-Science. | Copeptin: May it be a novel biomarker for insulin theraphy in diabetes? An animal study.[Ejmanager: Source] |
| Psychiatry and Clinical Neurosciences | Serum copeptin in children exposed to maltreatment[Pubmed:27278269] |
| United States Patent Application | Methods for Diagnosis and Treatment of Concussion or Brain Injury[2016:0103140] |
| J Physiol | Role of enteroendocrine L‐cells in arginine vasopressin‐mediated inhibition of colonic anion secretion[Pubmed:27037495] |
| International Journal of Clinical and Experimental Medicine | Can hypoxia enhance sexual arousal?-Molecular-biological analysis of the hypothalamus in male rats placed with oestrous female rats under hypoxic …[files:ijcem0031358.pdf] |
| Front Physiol | Orthostatic Challenge Shifts the Hemostatic System of Patients Recovered from Stroke toward Hypercoagulability.[pubmed:28223937] |
| Kidney Blood Pressure Research | N-Terminal Prohormone of Brain Natriuretic Peptide but not C-Terminal Pre-Pro Vasopressin (Copeptin) Level is Associated with the Response to Antihypertensive …[pubmed:29190613] |
| Hindawi Publishing Corporation | Early Prediction of Preeclampsia[journals:297397] |
| Journal of Urology | Evaluation of Urinary Aquaporin 2 and Plasma Copeptin as Biomarkers of Effectiveness of Desmopressin Acetate for the Treatment of Monosymptomatic Nocturnal Enuresis.[pubmed:28457803] |
| American Journal of Physiology-Renal?Physiology | Experimental Heat Stress Nephropathy and Liver Injury are Improved by Allopurinol[Pubmed:29667911] |
| American Journal of Physiology-Regulatory Integrative and Comparative Physiology | Angiotensin AT Receptors Expressed in Vasopressin-Producing Cells of the Supraoptic Nucleus Contribute to the Osmotic Control of Vasopressin[Pubmed:29364700] |
| BMC?Nephrology | Rehydration with fructose worsens dehydration-induced renal damage[Pubmed:30005632] |
| Experimental and Therapeutic?Medicine | Copeptin level in the early prediction of cardiorenal syndrome in rats[Pubmed:30112047] |
| 中國(guó)病理生理雜志 | 和肽素水平對(duì)大鼠心腎綜合征的早期預(yù)測(cè)價(jià)值[filename:ZBLS201802013] |
| Hypertension | Abstract P311: Static Urine Osmolality With Elevated First Trimester Urine Copeptin in Human Preeclampsia[] |
| Journal of Pediatric Urology | Assessment of serum levels of copeptin and corticotropin-releasing factor in children with monosymptomatic and nonmonosymptomatic nocturnal enuresis[] |
| experimental physiology | Cognitive performance is associated with cerebral oxygenation and peripheral oxygen saturation, but not plasma catecholamines, during graded normobaric hypoxia[] |
| international urology and nephrology | Dialysate copeptin and peritoneal transport in incident peritoneal dialysis patients[Pubmed: 31187425] |
| American Journal of Physiology-renal Physiology | The contribution of collecting duct NOS1 to the concentrating mechanisms in male and female mice[Pubmed: 31241990] |
| american journal of physiology-renal physiology | The increase of core temperature affected the progression of kidney injury by repeated heat stress exposure[Pubmed: 31390229] |
| Scientific Reports | Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion[Pubmed: 31863073] |
| BMC Nephrology | Copeptin is independently associated with vascular calcification in chronic kidney disease stage 5[Pubmed: 32033584] |
| Archives of Biochemistry and Biophysics | Micro RNA 146a gene variant/TNF-α/IL-6/IL-1 β; A cross-link axis inbetween oxidative stress, endothelial dysfunction and neuro-inflammation in acute ischemic stroke …[Pubmed: 31738890] |
| Ann Nutr Metab | Copeptin and Nesfatin-1 Are Interrelated Biomarkers with Roles in the Pathogenesis of Insulin Resistance in Chinese Children with Obesity[Pubmed: 33027789] |
| Biomolecules . | Multimarker Approach to Identify Patients with Coronary Artery Disease at High Risk for Subsequent Cardiac Adverse Events: The Multi-Biomarker Study[Pubmed: 32549327] |
| Arch Med Res | Relation of Copeptin with Diabetic and Renal Function Markers Among Patients with Diabetes Mellitus Progressing Towards Diabetic Nephropathy[Pubmed: 32505416] |
| 河北醫(yī)科大學(xué)學(xué)報(bào) | 重組人腦利鈉肽治療慢性肺心病急性加重期的臨床效果及對(duì)5-HT 濃度的影響[] |
| Scientific reports | Validity of different copeptin assays in the differential diagnosis of the polyuria-polydipsia syndrome[33980941] |
| International Journal of Women?ˉs Health and Reproduction Sciences | Are the Circulating Levels of Copeptin and Fibronectin Dysregulated in Preeclamptic South African Black Women?[] |
| Dicle T?p Dergisi | Copeptin levels are more elevated and associated with cardiovascular events in the unity of chronic ischemic heart and chronic kidney diseases[] |
| High serum copeptin may be a marker of an increased carotid intima-media thickness in asymptomatic patients with type 1 diabetes.[] | |
| Nutrients | The Speed of Ingestion of a Sugary Beverage Has an Effect on the Acute Metabolic Response to Fructose[] |
| Acta Physiol (Oxf) | Dietary K+ acts as a genuine diuretic[Pubmed:34984847] |
| Anal Chim Acta | Spectrally multiplexed assay using gap enhanced nanoparticle for detection of a myocardial infarction biomarker panel[Pubmed:35190126] |
| J Cell Physiol | Arcuate NPY is involved in salt‐induced hypertension via modulation of paraventricular vasopressin and brain‐derived neurotrophic factor[Pubmed:35312067] |
| Children | Copeptin Concentrations in Plasma of Healthy Neonates in Relation to Water–Electrolyte Homeostasis in the Early Adaptation Period[Pubmed:35327814] |