信號(hào)素4D(SEMA4D)重組蛋白
Recombinant Semaphorin 4D (SEMA4D)
CD100; A8; BB18; GR3; M-Sema G; M-Sema-G; SEMAJ; Coll-4; Sema Domain,Immunoglobulin Domain(Ig),Transmembrane Domain(TM)and Short Cytoplasmic Domain 4D
- 編號(hào)RPB430Ra01
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞質(zhì), 細(xì)胞外基質(zhì)
- 預(yù)測(cè)分子量68.9kDa
- 實(shí)際分子量69kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Leu145~Gly494 with N-terminal His and GST Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)7.2
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格¥ 1123¥ 2808¥ 5616¥ 16848¥ 42120
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
SDS-PAGE圖
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB430Ra01 | 信號(hào)素4D(SEMA4D)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB430Ra01 | 信號(hào)素4D(SEMA4D)多克隆抗體 | WB; IHC; ICC; IP. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Expert Opin Ther Targets. | Circulating semaphorin-4D and plexin-B1 levels in postmenopausal women with low bone mass: the 3-month effect of zoledronic acid, denosumab or teriparatide treatment[Pubmed:25395071] |
| Obesity (Silver Spring). | Genome-wide analysis identifies an african-specific variant in SEMA4D associated with body mass index.[pubmed:28296344] |
| Clinical Lymphoma, Myeloma & Leukemia | A Revised Staging System for Waldenstr?m's Macroglobulinemia[10.1016/j.clml.2017.07.146] |
| Clinical Lymphoma, Myeloma & Leukemia | Extramedullary Multiple Myeloma: Clinical Features and Prognosis in Argentina[10.1016/j.clml.2017.07.144] |
| Blood?Cancer?Journal | Semaphorin 4D correlates with increased bone resorption, hypercalcemia, and disease stage in newly diagnosed patients with multiple myeloma[Pubmed:29748532] |
| Analytical Biochemistry | A high-sensitivity enzyme immunoassay for the quantification of soluble human semaphorin 4D in plasma[Pubmed: 30879960] |
| Journal of Allergy and Clinical Immunology-In Practice | Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis[Pubmed: 32035658] |