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抗親環(huán)素A(CYPA)單克隆抗體

Anti-Cyclophilin A (CYPA) Monoclonal Antibody

PPIA; CyP-A; CYPH; Peptidylprolyl Isomerase A; Peptidyl-Prolyl Isomerase A; Peptidyl-prolyl cis-trans isomerase A; Cyclosporin A-binding protein

  • 抗親環(huán)素A(CYPA)單克隆抗體產(chǎn)品包裝(模擬)
  • 抗親環(huán)素A(CYPA)單克隆抗體產(chǎn)品包裝(模擬)
  • 抗親環(huán)素A(CYPA)單克隆抗體DAB staining on IHC-P; Sample: Mouse Kidney Tissue; Primary Ab: 30μg/ml Mouse Anti-Multi-species CYPA Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • 抗親環(huán)素A(CYPA)單克隆抗體DAB staining on IHC-P;
    Sample: Mouse Small intestine Tissue;
    Primary Ab: 30μg/ml Mouse Anti-Multi-species CYPA Antibody
    Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • CAA979Mi22.jpgWB圖
  • 抗親環(huán)素A(CYPA)單克隆抗體Western Blot; Sample: Lane1: Mouse Cerebrum lysate; Lane2: Mouse Liver lysate; Lane3: Mouse Testis lysate; Lane4: HepG2 cell lysate; Lane5: Jurkat cell lysate
    Primary Ab: 2μg/ml Mouse Anti-Mouse CYPA Antibody
    Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody
    (Catalog: SAA544Mu19)
  • Certificate通過ISO 9001、ISO 13485質(zhì)量體系認證

特異性

該抗體是針對CYPA的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別CYPA。

用法

免疫印跡：0.2-2μg/mL;1:500-5000
免疫組織化學：5-20μg/mL;1:50-200
免疫細胞化學：5-20μg/mL;1:50-200
最佳稀釋倍數(shù)最終由用戶決定。

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。

贈品

相關產(chǎn)品

編號適用物種：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠)應用(僅供研究使用，不用于臨床診斷！)
CAA979Mi22抗親環(huán)素A(CYPA)單克隆抗體WB; IHC

參考文獻

雜志參考文獻
AtherosclerosisEMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation[PubMed: 19758589]
BiomarkersCyclophilin-A: a novel biomarker for untreated male essential hypertension[Pubmed: 24164594]
Cardiovascular DiabetologyPlasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease[Pubmed:24502618]
International Journal of Biological SciencesDecrease in Plasma Cyclophilin A Concentration at 1 Month after Myocardial Infarction Predicts Better Left Ventricular Performance and Synchronicity at 6 Months: A Pilot Study in Patients with ST Elevation Myocardial Infarction[Pubmed:25552928]
MedicineCyclophilin A in Ruptured Intracranial Aneurysm[PubMed: 26426668]
Mol Cell BiochemPPIA rs6850: A> G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease[PubMed: 26702934]
Medicine (Baltimore)Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus[PubMed: 26496315]
International Journal of CardiologyCyclophilin?A?modulates?bone?marrow-derived?CD117(+)?cells?and?enhances?ischemia-induced?angiogenesisvia?the?SDF-1/CXCR4?axis.[Pubmed:27057951]
Clinica?Chimica?ActaNovel findings of secreted cyclophilin A in diabetic nephropathy and its association with renal protection of dipeptidyl peptidase 4 inhibitor[pubmed:27823952]
Cardiovascular?DiabetologyCyclophilin?A?enhances?macrophage?differentiation?and?lipid?uptake?in?high?glucose?conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus.[pubmed:27809851]
Clinical?ScienceMetformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity[Pubmed:29382697]
Journal of Molecular HistologyCyclophilin a increases CD68 cell infiltration in rat experimental periodontitis[Pubmed:29318411]
Free?Radical?ResearchCyclophilin A and CD147 associate with progression of diabetic nephropathy[Pubmed: 30572748]
The Kaohsiung Journal of Medical SciencesAssociation of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction[Pubmed: 31670477]
Cells.Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients[Pubmed: 31936351]
JAMA NeurologyAPPENDIX A: Relationship between cyclophilin A levels and matrix metalloproteinase-9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers?…[Pubmed: 24030206]
Menoufia Medical JournalUrinary podocalyxin and cyclophilin A: markers for early detection of type 2 diabetic nephropathy[]
ToxinsEvaluation of the Therapeutic Effects of Protocatechuic Aldehyde in Diabetic Nephropathy[34437430]
Cell Death & DiseaseProteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death[Pubmed:35732625]