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中性粒細(xì)胞彈性蛋白酶(NE)單克隆抗體

Monoclonal Antibody to Neutrophil Elastase (NE)

ELANE; HLE; HNE; ELA2; PMN-E; Neutrophil Elastase; Medullasin; Polymorphonuclear Leukocyte Elastase; Bone Marrow Serine Protease; Leukocyte Elastase; PMN Elastase

  • 中性粒細(xì)胞彈性蛋白酶(NE)單克隆抗體產(chǎn)品包裝(模擬)
  • 中性粒細(xì)胞彈性蛋白酶(NE)單克隆抗體產(chǎn)品包裝(模擬)
  • Certificate通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對NE的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別NE。

用法

Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲,損失率低于5%。

贈品

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編號適用物種:Homo sapiens (Human,人)應(yīng)用(僅供研究使用,不用于臨床診斷!)
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參考文獻(xiàn)

雜志參考文獻(xiàn)
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Journal of Photochemistry and Photobiology B: BiologyA dietary supplement improves facial photoaging and skin sebum, hydration and tonicity modulating serum fibronectin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins[Pubmed:25732262]
International Journal of Molecular MedicineThe neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats[pubmed:27430552]
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Clin Exp Pharmacol Physiol.Inhibition of ALDH2 protects PC12 cells against formaldehyde-induced cytotoxicity: involving the protection of hydrogen sulphide.[pubmed:28251688]
Journal of CardiologyTargeted regulation of sympathetic activity in paraventricular nucleus reduces inducible ventricular arrhythmias in rats after myocardial infarction[10.1016:j.jjcc.2018.06.003]
NeuroscienceAngiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats[Pubmed:29684507]
Molecular and Cellular BiochemistryRepetitive transcranial magnetic stimulation inhibits Sirt1/MAO-A signaling in the prefrontal cortex in a rat model of depression and cortex-derived astrocytes[Pubmed:28948423]
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Journal of Clinical ImmunologyMiR-608 Exerts Anti-inflammatory Effects by Targeting ELANE in Monocytes[Pubmed: 31749032]
Pathology & Oncology ResearchNeutrophil Extracellular Traps Associate with Clinical Stages in Breast Cancer[Pubmed: 31656990]
Bioscience ReportsInhibition of microRNA-146a attenuated heart failure in myocardial infarction rats[Pubmed: 31763669]
Oxidative Medicine and Cellular LongevityNeutrophil Elastase Inhibitors Suppress Oxidative Stress in Lung during Liver Transplantation[Pubmed: 31871555]
CytokineLevels of pro-and anti-inflammatory cytokines in cystic fibrosis patients with or without gingivitis[Pubmed: 31927460]
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CLINICAL AND EXPERIMENTAL HYPERTENSIONHyperinsulinemia rather than insulin resistance itself induces blood pressure elevation in high fat diet-fed rats[Pubmed: 32349626]
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Evidence-Based Complementary and Alternative MedicineZisheng Shenqi Decoction Ameliorates Monosodium Urate-Mediated Gouty Arthritis in Rats via Promotion of Autophagy through the AMPK/mTOR Signaling??-[33505502]
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Neuromodulation: Technology at the Neural InterfaceTranscutaneous Electrical Acustimulation Improved the Quality of Life in Patients With Diarrhea-Irritable Bowel Syndrome[Pubmed:35088760]
A Novel Role of Tinospora Cordifolia in Amelioration of Cancer-Induced Systemic Deterioration By Taming Neutrophil Infiltration and Hyperactivation[]