粘蛋白5B(MUC5B)多克隆抗體(生物素標(biāo)記)
Biotin-Linked Polyclonal Antibody to Mucin 5 Subtype B (MUC5B)
MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin
- 編號(hào)LAA684Hu71
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來源抗體標(biāo)記
- Ig類型IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物生物素
- 原抗體PAA684Hu01-粘蛋白5B(MUC5B)多克隆抗體
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度500μg/mL
- 且適物種-
- 應(yīng)用WB; IHC; ICC.
如果抗體需用于流式細(xì)胞術(shù)，請(qǐng)參見流式抗體。 - 下載英文說明書 中文說明書
- 規(guī)格20μl100μl200μl1ml10ml
- 價(jià)格¥ 623¥ 1453¥ 2076¥ 5190¥ 20760
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對(duì)MUC5B的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別MUC5B。
用法
Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
贈(zèng)品
增值服務(wù)
Protein-A/G純化柱
細(xì)胞和組織染色液
抗體陽性對(duì)照品
組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
DAB顯色試劑盒
SABC試劑盒
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA684Hu02 | 粘蛋白5B(MUC5B)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA684Hu01 | 粘蛋白5B(MUC5B)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPA684Hu21 | 粘蛋白5B(MUC5B)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
| PAA684Hu01 | 粘蛋白5B(MUC5B)多克隆抗體 | WB |
| PAA684Hu02 | 粘蛋白5B(MUC5B)多克隆抗體 | WB; IHC; ICC; IP. |
| LAA684Hu81 | 粘蛋白5B(MUC5B)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| LAA684Hu71 | 粘蛋白5B(MUC5B)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| MAA684Hu27 | 粘蛋白5B(MUC5B)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA684Hu28 | 粘蛋白5B(MUC5B)單克隆抗體 | IHC |
| MAA684Hu21 | 粘蛋白5B(MUC5B)單克隆抗體 | WB; IHC; ICC; IP. |
| MAA684Hu22 | 粘蛋白5B(MUC5B)單克隆抗體 | WB |
| MAA684Hu23 | 粘蛋白5B(MUC5B)單克隆抗體 | IHC |
| MAA684Hu24 | 粘蛋白5B(MUC5B)單克隆抗體 | IHC |
| MAA684Hu25 | 粘蛋白5B(MUC5B)單克隆抗體 | IHC |
| MAA684Hu29 | 粘蛋白5B(MUC5B)單克隆抗體 | WB; IHC; ICC; IP. |
| SEA684Hu | 粘蛋白5B(MUC5B)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA684Hu | 粘蛋白5B(MUC5B)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMA684Hu | 粘蛋白5B(MUC5B)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| The Journal of Biological Chemistry | The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling[Jcb: 34199] |
| The Journal of Biological Chemistry | The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling[Jcb: 247684] |
| Respiratory Researh | Pyocyanin-induced mucin production is associated with redox modification of FOXA2[PubMed: PMC3765780] |
| Respirology | Secreted mucins and airway bacterial colonization in non-CF bronchiectasis[PubMed: 26172851] |
| American Thoracic Society International Conference Abstracts | Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness[doi:10.1164] |
| Ann Am Thorac Soc | Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization[doi:10.1513] |
| Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой[10.20538/1682-0363-2017-2-146-158] | |
| Allergy | Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps[Pubmed:29802623] |
| European?Journal of Pharmacology? | Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling[Pubmed:29382534] |
| Japan Society of Immunology & Allergology in Otolaryngology | インフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響[10.5648:jjiao.36.7] |
| Journal of Investigative?Medicine | The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease[Pubmed: 30573494] |
| Mucosal Immunology | ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism[Pubmed: 31278375] |