前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體
Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
FH3; HCHOLA3; NARC1; Hypercholesterolemia,Autosomal Dominant 3; Neural apoptosis-regulated convertase 1; Proprotein convertase 9; Subtilisin/kexin-like protease PC9
- 編號MAE189Ra22
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C2
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原RPE189Ra01-前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度1mg/mL
- 且適物種-
- 應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載英文說明書 中文說明書
- 規(guī)格20μl100μl200μl1ml10ml
- 價格¥ 745¥ 1739¥ 2484¥ 6210¥ 24840
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
IHC圖
Western Blot; Sample: Jurkat cell lysate Primary Ab: 2μg/ml Mouse Anti-Rat PCSK9 Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對PCSK9的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別PCSK9。
用法
Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPE189Ra01 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAE189Ra01 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)多克隆抗體 | WB; IHC; ICC; IP. |
| MAE189Ra23 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB; IHC; ICC; IP. |
| MAE189Ra22 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB; IHC; ICC; IP. |
| MAE189Ra21 | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | WB; IHC |
| FAE189Ra02 | 抗前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)單克隆抗體 | Flow cytometry. |
| SEE189Ra | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LME189Ra | 前蛋白轉(zhuǎn)化酶枯草溶菌素9(PCSK9)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Biological Trace Element Research | Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers[pubmed:28409410] |
| BASIC RESEARCH IN CARDIOLOGY | Autocrine effects of PCSK9 on cardiomyocytes[Pubmed: 33169229] |
| J Transl Med | Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans[33407555] |
| Metabolism | MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice[33775647] |
| Eur Rev Med Pharmacol Sci | Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders[34533801] |
| Clin Exp Hypertens | Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease[Pubmed:35502687] |